Physical activity and exercise in children and adolescents with epilepsy
DOI:
https://doi.org/10.5281/zenodo.13381276Keywords:
Adolescent, child, epilepsy, physical activity, sportsAbstract
Epilepsy is defined as a brain disorder characterized by epileptic seizures. Children with epilepsy are less physically active than the general population. The most common reasons are prejudice, overprotection, unconsciousness, stigma, and fear of triggering a seizure. Studies indicate that exercise contributes to a decrease in the frequency and severity of seizures in children with epilepsy. In addition, regular exercises were found to be beneficial for maximum aerobic capacity and self-confidence. With increasing evidence on the subject, it is important to include children and adolescents with epilepsy in individualized regular physical activity and exercise programs. This review aims to provide information about the risks and benefits associated with physical activity and exercise in this patient group.
References
Abel, J.L.B. & Rissman, E.F(2013). Running-induced epigenetic and gene expression changes in the adolescent brain. Int J Dev Neurosci, 31, 382–90, https://doi.org/10.1016/j.ijdevneu.2012.11.002.
Allendorfer, J.B. & Arida, R.M(2018). Role of physical activity and exercise in alleviating cognitive impairment in people with epilepsy. Clin Ther, 40, 26–34. https://doi.org/10.1016/j.clinthera.2017.12.004.
Allendorfer, J.B., Brokamp, G.A., Nenert, R., Szaflarski, J.P., Morgan, C.J……..& Tuggle, S.C(2019). A pilot study of combined endurance and resistance exercise rehabilitation for verbal memory and functional connectivity improvement in epilepsy. Epilepsy Behav, 96, 44–56. https://doi.org/10.1016/j.yebeh.2019.04.020.
Anderson, B. J., Li, X., Alcantara, A. A., Isaacs, K. R., Black, J. E. & Greenough, W. T. (1994). Glial hypertrophy is associated with synaptogenesis following motor-skill learning, but not with angiogenesis following exercise. Glia, 11(1), 73–80. https://doi.org/10.1002/glia.440110110.
Arida, R.M., Cavalheiro, E.A., Da Silva, A.C. & Scorza, F.A(2008). Physical activity and epilepsy: proven and predicted benefits. Sport Med, 38, 607–15. https://doi.org/10.2165/00007256-200838070-00006.
Arida, R.M., Cavalheiro, E.A. & Scorza, F.A(2012). From depressive symptoms to depression in people with epilepsy: contribution of physical exercise to improve this picture. Epilepsy Research, 99(1-2), 1-13. https://doi.org/10.1016/j.eplepsyres.2011.10.012
Arida, R.M., Scorza, F.A., da Silva, S.G., Schachter, S.C. & Cavalheiro, E.A(2010). The potential role of physical exercise in the treatment of epilepsy. Epilepsy & Behavior, 17(4), 432-5. https://doi.org/10.1016/j.yebeh.2010.01.013
Arida, R. M., Scorza, F. A., Gomes da Silva, S., Cysneiros, R. M. & Cavalheiro, E. A. (2011). Exercise paradigms to study brain injury recovery in rodents. American Journal of Physical Medicine & Rehabilitation, 90(6), 452–465. https://doi.org/10.1097/PHM.0b013e318206
Arida, R. M., Scorza, F. A., Toscano-Silva, M. & Cavalheiro, E. A. (2010). Does exercise correct dysregulation of neurosteroid levels induced by epilepsy?. Annals of Neurology, 68(6), 971–972. https://doi.org/10.1002/ana.22086
Bay, Ü. S. & Yılmaz, E. (2020). Ruhsal Bozukluklarda Fiziksel Aktivite ve Egzersizin Etkileri ile İlgili Yapılmış Çalışmaların İncelenmesi. Akdeniz Spor Bilimleri Dergisi, 3(2), 437-447. https://doi.org/10.38021/asbid.849274
Bjørholt, P. G., Nakken, K. O., Røhme, K. & Hansen, H. (1990). Leisure time habits and physical fitness in adults with epilepsy. Epilepsia, 31(1), 83–87. https://doi.org/10.1111/j.1528-1157.1990.tb05364.x
Brna, P. M., Gordon, K. E., Woolridge, E., Dooley, J. M. & Wood, E. (2017). Perceived need for restrictions on activity for children with epilepsy. Epilepsy & Behavior: E&B, 73, 236–239. https://doi.org/10.1016/j.yebeh.2017.05.012
Camfield, P. R. & Camfield, C. S. (2014). What happens to children with epilepsy when they become adults? Some facts and opinions. Pediatric Neurology, 51(1), 17–23. https://doi.org/10.1016/j.pediatrneurol.2014.02.020
Carrizosa-Moog, J., Ladino, L.D., Benjumea-Cuartas, V., Orozco-Hernández, J.P., Castrillón-Velilla D.M…………. & Rizvi S.(2018). Epilepsy, physical activity and sports: a narrative review. Can J Neurol Sci, 45, 624–632. https://doi.org/10.1017/cjn.2018.34
Cavalcante, B. R. R., Improta-Caria, A. C., Melo, V. H. & De Sousa, R. A. L. (2021). Exercise-linked consequences on epilepsy. Epilepsy & Behavior: E&B, 121(Pt A), 108079. https://doi.org/10.1016/j.yebeh.2021.108079
Contet, C., Gavériaux-Ruff, C., Matifas, A., Caradec, C., Champy, M. F. & Kieffer, B. L. (2006). Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 31(8), 1733–1744. https://doi.org/10.1038/sj.npp.1300934
Drazkowski, J. F. (2003). Management of the social consequences of seizures. In Mayo Clinic Proceedings, 78(5), 641-649.
Dubow, J. S. & Kelly, J. P. (2003). Epilepsy in sports and recreation. Sports Medicine, 33, 499-516. https://doi.org/10.2165/00007256-200333070-00003
Fisher, R. S., van Emde Boas, W., Blume, W., Elger, C., Genton, P., Lee, P. & Engel Jr, J.(2005). Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia, 46(4), 470–472. https://doi.org/10.1111/j.0013-9580.2005.66104.x
Freitas, D.A., Rocha-Vieira, E., De Sousa, R.A.L., Soares, B.A., Rocha-Gomes, A……. & Chaves Garcia BC.(2019). High-intensity interval training improves cerebellar antioxidant capacity without affecting cognitive functions in rats. Behav Brain Res, 376, https://doi.org/10.1016/j.bbr.2019.112181112181
Gomes da Silva, S., de Almeida, A. A., Silva Araújo, B. H., Scorza, F. A., Cavalheiro, E. A. & Arida, R. M. (2011). Early physical exercise and seizure susceptibility later in life. International Journal of Developmental Neuroscience: The Official Journal of The International Society for Developmental Neuroscience, 29(8), 861–865. https://doi.org/10.1016/j.ijdevneu.2011.07.011
Gómez-Pinilla, F., So, V. & Kesslak, J. P. (1998). Spatial learning and physical activity contribute to the induction of fibroblast growth factor: neural substrates for increased cognition associated with exercise. Neuroscience, 85(1), 53–61. https://doi.org/10.1016/s0306-4522(97)00576-9
Gould, E., Beylin, A., Tanapat, P., Reeves, A. & Shors, T. J. (1999). Learning enhances adult neurogenesis in the hippocampal formation. Nature Neuroscience, 2(3), 260–265. https://doi.org/10.1038/6365
Gür, H. & Küçükoğlu, S., (1992). Yaşlılık ve Fiziksel Aktivite, Roche Yayınları, 9
Häfele, C. A., Rombaldi, A. J., Feter, N., Häfele, V., Gervini, B. L., Domingues, M. R. & da Silva, M. C. (2021). Effects of an exercise program on health of people with epilepsy: A randomized clinical trial. Epilepsy & Behavior: E&B, 117, 107904. https://doi.org/10.1016/j.yebeh.2021.107904
Hammers, A., Asselin, M. C., Hinz, R., Kitchen, I., Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007). Upregulation of opioid receptor binding following spontaneous epileptic seizures. Brain: A Journal of Neurology, 130(4), 1009–1016. https://doi.org/10.1093/brain/awm012
McAuley, J. W., Long, L., Heise, J., Kirby, T., Buckworth, J., Pitt, C., Lehman, K. J., Moore, J. L. & Reeves, A. L. (2001). A Prospective Evaluation of the Effects of a 12-Week Outpatient Exercise Program on Clinical and Behavioral Outcomes in Patients with Epilepsy. Epilepsy & Behavior: E&B, 2(6), 592–600. https://doi.org/10.1006/ebeh.2001.0271
Melo, C.S., Rocha-Vieira, E., Freitas, D.A., Soares, B.A., Rocha-Gomes, A….. & Riul, TR.(2019). A single session of high-intensity interval exercise increases antioxidants defenses in the hippocampus of Wistar rats. Physiol Behav, 211, https://doi.org/10.1016/j.physbeh.2019.112675.
Mika, A., Macaluso, F., Barone, R., Di Felice, V. & Sledzinski, T.(2019). Effect of exercise on fatty acid metabolism and adipokine secretion in adipose tissue. Front Physiol, 10, 26. https://doi.org/10.3389/fphys.2019.00026
Nakken, K.O., Bjørholt, P.G., Johannessen, S.I., LoSyning, T. & Lind, E.(1990). Effect of physical training on aerobic capacity, seizure occurrence, and serum level of antiepileptic drugs in adults with epilepsy. Epilepsia, 31, 88–94. https://doi.org/10.1111/j.15281157.1990.tb05365.
Neeper, S. A., Gómez-Pinilla, F., Choi, J. & Cotman, C. (1995). Exercise and brain neurotrophins. Nature, 373(6510), 109. https://doi.org/10.1038/373109a0
Pimentel, J., Tojal, R. & Morgado, J. (2015). Epilepsy and physical exercise. Seizure, 25, 87–94. https://doi.org/10.1016/j.seizure.2014.09.015
Sırtbaş, G., Yalnızoğlu, D. & Livanelioğlu, A. (2021). Comparison of physical fitness, activity, and quality of life of the children with epilepsy and their healthy peers. Epilepsy Research, 178, 106795. https://doi.org/10.1016/j.eplepsyres.2021.106795
Sutoo, D. & Akiyama, K.(2003). Regulation of brain function by exercise. Neurobiol Dis, 13, 1–14. https://doi.org/10.1016/S0969-9961(03)00030-5.
Wang, R. Y., Yang, Y. R. & Yu, S. M. (2001). Protective effects of treadmill training o infarction in rats. Brain Research, 922(1), 140–143. https://doi.org/10.1016/s00068993(01)03154-7.
Whitney, R., Bhan, H., Persadie, N., Streiner, D., Bray, S. & Timmons, B.(2013). Feasibility of pedometer use to assess physical activity and its relationship with quality of life in children with epilepsy: A pilot study. Pediatric Neurology, 49(5), 370-3.
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